報告題目:Relation between blood pressure and pulse wave velocity for human arteries
報告人: 黃永剛教授 美國西北大學
報告時間:2019年4月18日(星期四)上午10:00-11:00
報告地點:浙江大學玉泉校區教12-118
報告摘要:
Continuous monitoring of blood pressure, an essential measure of health status, typically requires complex, costly, and invasive techniques that can expose patients to risks of complications. Continuous, cuffless, and noninvasive blood pressure monitoring methods that correlate measured pulse wave velocity (PWV) to the blood pressure via the Moens−Korteweg (MK) and Hughes Equations, offer promising alternatives. The MK Equation, however, involves two assumptions that do not hold for human arteries, and the Hughes Equation is empirical, without any theoretical basis. The results presented here establish a relation between the blood pressure P and PWV that does not rely on the Hughes Equation nor on the assumptions used in the MK Equation. This relation degenerates to the MK Equation under extremely low blood pressures, and it accurately captures the results of in vitro experiments using artificial blood vessels at comparatively high pressures. For human arteries, which are well characterized by the Fung hyperelastic model, a simple formula between P and PWV is established within the range of human blood pressures. This formula is validated by literature data as well as by experiments on human subjects, with applicability in the determination of blood pressure from PWV in continuous, cuffless, and noninvasive blood pressure monitoring systems.
報告人簡介:
黃永剛,美國工程院院士、中國科學院外籍院士、歐洲科學院外籍院士、美國西北大學Walter P. Murphy講席教授。他的研究領域是可延展和柔性電子力學、力學引導的三維結構組裝等,并撰寫了兩部專著、發表了500多篇SCI論文,包括10篇Science和4篇Nature。近年來他獲得美國機械工程師協會的Drucker Medal (2013)和Nadai Medal (2016)、工程科學學會的Prager Medal (2017)、材料科學領域的高被引作者(since 2014) 和物理學領域的高被引作者(since 2018)、美國土木工程師協會的Bazant Medal (2018)等。